I remember only one scene. The characted played by Robert De Niro (or Dustin Hoffman or somebody similar) is virgin man. He saw fat woman (perhaps prostitute), which was friend of other person (perhaps his friend). Then, they have sex (although it wasn’t showed probably) and he is glad, because it was his first time. It was typical road movie and I’m sure that it was during long travel and rather action movie than only comedy. The character is 35-40 years old, I think.
Perhaps it was action movie (or comedy) from 90s or 2000s. Definitely USA. Perhaps it’s Mandela Effect and it isn’t any of these actors, but I’m sure mentioned scene.
New information:
I remember his friend/brother asking him: “Did you like it?” he replies: “Yes, it was great.” She says goodbye to him and moves on with her friend or brother, I think. It might have been at some motel.